antiaging biotechnology collagen elastin extracellularmatrix peptides science Skin management System by Dr. Strauss

Biotechnology Advancements and Their Implications in the Cosmetic Industry: Part II – Skin Management System by Dr. Strauss

October 17, 2019

The key behind the development of efficacious skin care ingredients is the knowledge of skin physiology acquired through research.

The number one factor which contributes to skin aging is sun exposure. This means that protecting your skin from the sun is your best bet to avoid premature skin aging, and also important to minimize your chances of skin cancer development.

The outermost layer of the skin, the epidermis, thins as we age. Regeneration of the epidermis is dependent on the ability of the stem cells to produce new skin cells (keratinocytes). As we age the activity of these cells decreases therefore the epidermis becomes thinner as fewer keratinocytes are being produced to maintain the thickness of the epidermis. With a thinner epidermis, our skin is more fragile and susceptible to injury and water loss which leaves our skin dehydrated.

In the dermis the effect of sun exposure causes elastosis, the breakdown of elastin, causing the skin to look leathery and furthering the development of fine lines. Fibroblasts also become less active as we age, resulting in less collagen and elastin being produced, leaving the skin looking thin and less firm. The breakdown of the extracellular matrix also leaves the blood vessels in the skin unprotected, and can lead to easy bruising, and bleeding.

Although it is found that the number of melanocytes in the skin decreases with age, the size of the remaining melanocytes increases. This means that with sun-exposure the production of melanin will appear uneven, producing large dark spots (age spots), that also appear more noticeable since the epidermis is thinner.

While properly protecting yourself from the sun will help prevent these negative effects, skin damage and aging is inevitable. Luckily, we now have a greater understanding of how skin physiology changes over time, which has allowed researchers to find innovative ways to intervene with the skin aging process. With new peptide technology, the activity of cells in the skin, and the production of extracellular matrix proteins can be optimized to improve the exterior appearance of the skin.

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Beautifully Yours,

Skin Management System by Dr. Strauss